The ARISE Project consortium is composed of 23 partner coming from EU (Italy, France, UK and Cyprus) and non-EU countries (Nigeria, Lebanon, Kenya and USA).
Guy’s & St. Thomas’ Hospital NHS Foundation Trust (UK)
Guy’s and St. Thomas’ NHS Foundation Trust (GSTT) is dedicated to providing high quality, personal care for all patients with this vision being at the heart of everything that the organisation does. In a recent survey, GSTT was the best performing London teaching Trust in the nation.
The Trust provides world-class sickle cell service for the single largest sickle cell patient population in Western Europe. Located in London, a full range of medical services is provided for local residents as well as specialist services for patients from further afield. Care takes place in two of London’s best-known teaching hospitals, Guy’s Hospital and St Thomas’ Hospital, where Evelina London Children’s Hospital is also located. The INPUT pain management centre provides a unique residential pain service which is one of only a few services in the world that has particular expertise in neuromodulation and spinal stimulator implantation.
The hospital system is part of King’s Health Partners (KHP) one of only six Academic Health Sciences Centres in England designated by the Department of Health. Through a joint venture with King’s College Hospital NHS Foundation Trust and Serono PLC, GSTT has strong links with Viapath, which is the UK’s largest provider of world-class pathology services.
The Trust is involved in a number of projects across specialities to improve wellbeing of patients. One of such projects include the GSTT Zambia Partnership which focuses on Sickle Cell, patient safety & infection control, Adolescent and maternal health.
With an exceptional history of excellent patient care and links to well renowned medical and teaching services, GSTT provides an excellent training platform to those willing to learn and contribute towards improving patient care.
Fondazione per la Ricerca Farmacologica Gianni Benzi onlus (Italy)
Fondazione Gianni Benzi (FGB) is a registered not-for-profit scientific research organisation promoting research in biological, medical and pharmaceutical areas, with particular reference to the needs of patients affected by rare diseases and other populations with specific therapeutic needs, including children. FGB activities are mainly focused on the regulatory, ethical and methodological support to research as well as on data science.
FGB participates in many national and international initiatives in which it contributes to the planning and conduct of interventional and non-interventional clinical studies, dealing with methodological aspects such as design, compliance with ethical and regulatory requirements, data collection and analysis, and IT tools set up (platforms, database, e-learning instruments, surveys). In many of these initiatives FGB is also in charge of project management.
Elaborating and revising guidelines and regulatory recommendations is one of the applications of the FGB methodological expertise.
Furthermore, FGB carries out Health Technology Assessment (HTA) reports including analysis on the use of drugs and other health technologies aimed at providing summaries and assessment of the available evidence, including PROs (Patient Reported Outcomes) and Quality of Life (QoL).
Haemoglobinopathies are one of the key topics of FGB, that has been managing the Italian Multinational Thalassemia Patients Registry for many years. FGB is partner of relevant international studies and patients’ data collection initiatives including beta-thalassemia, Sickle Cell Diseases and other rare Haemoglobinopathies.
Several resources are invested for patients’ empowerment, supporting them in becoming protagonists in the development of new medicines and therapies as well as in the appropriate use of existing ones.
FGB activities are also addressed to dissemination, education and training (e.g. the yearly Foresight Training Course, a high-level specialised short course) devoted at spreading new and existing knowledge, also considering European strategies in the regulatory field.
Lagos State University (Nigeria)
Lagos State University (LASU) Badagry Road, Ojo was established as a public University 1983 enabled by the Lagos State law. The College of Medicine was established 20 years ago and is situated on the same premises as the affiliate Lagos State University Teaching Hospital (LASUTH) in Ikeja, Lagos.
It is also 10 min drive from the Lagos Murhtala Muhammed International airport.
The hospital and College of Medicine (LASUCOM) jointly are well staffed and equipped to support robust activities of clinical subspecialties of Dentistry, Surgery, Medicine, Paediatrics, Obstetrics and Gynaecology and support services.
The teaching hospital has well developed radiological and laboratory services for studies in Microbiology, Chemistry, Haematology and currently setting up a molecular research laboratory.
We have robust blood banking services upon which the hospital and large sections of the State rely. LASUTH has over 600 beds and Intensive care Unit and Critical Care Unit. The hospital has a helipad for air evacuation and receipt of airlifted patients.
Our adult and paediatric Sickle Cell clinics have over 1000 patients each and an adolescent transition clinic is currently being developed. Our hospital facilities and services are accredited by the Medical and Dental Council of Nigeria, the Nigerian Universities Commission, the National and West African Postgraduate Colleges of Medicine and of Surgery for undergraduate and postgraduate medical training.
University of Abuja (Nigeria)
The University of Abuja (UA) is a government owned University located in Abuja, Nigeria’s Federal Capital.
The University was established on the 1st day of January 1988 (UA Act of 1992 No 106). There are 10 Faculties in the University namely: College of Heath Sciences, Faculties of Agriculture, Arts, Education, Engineering, Law, Management Sciences, Science, Social Sciences and Veterinary Medicine. All courses are accredited by the National Universities Commission (NUC). In addition the College of Health Sciences (CHS) is also accredited by Medical and Dental council of Nigeria (MDCN).
The UA is a young university which has developed from one of the least in Nigeria to the top 10 in just about 2 decades of its establishment, largely due to excellent management and location at Abuja FCT, thus the UA is attractive to the academics, students and partners alike. The current Vice chancellor of the University is Professor Abdulrasheed Na’Allah.
The University of Abuja Teaching Hospital (UATH) is affiliated to the University of Abuja. The teaching hospital has a total of 133 Clinical specialist consultants in various specialties of human medicine. The Chief Medical Director is Professor Bisalla A. Ekele.
The University of Abuja thus has very great potential to become one of the leading universities in Africa and globally. Abuja the Federal Capital Territory (FCT) is multi ethnic, multi religious and home for all Nigerians. FCT has great social life and security and is therefore also suitable for international staff exchanges, tourists and visitors.
University of Ilorin (Nigeria)
University of Ilorin & University of Iloin Teaching Hospital are both public institutions operating specialist care centre for patients with Sickle Cell Disease in Nigeria. Professor Kolade Ernest, MBBS, Cert Health Plann & Mgt., FWACP, MNIM, FRCPCH, provides leadership for the University of Ilorin Team.
University of Ilorin established several Community surveillance (COBES) centre that have been used over several years, a new TCD machine just installed, Malaria Centre is an independent premise solely for research and Bactec Machine for Microbiology. Few of Previous. Research involvement: UNICEF Acute Respiratory infection project, National micronutrient survey, AQUAMAT project that led to antimalarial global policy change by WHO, Randomised clinical trial of 3 antimalarial chemoprophylaxis among SCD patients, Mass Haemoglobin screening of Primary school pupils, Hepatitis B infection among SCD children, Hepatitis C infection among SCD children, G6PD Screening among SCD children. WHO Polio Vaccine (OPV/IPV) Randomized Clinical Trial. Currently many research activities are also going on, including; Comparativeness of Mercury and Infra-red non-touch Thermometers, National Rotavirus surveillance and Assessment of Quality of Life and hospital services among SCD patients.
International Foundation Against Infectious Disease in Nigeria – IFAIN (Nigeria)
IFAIN is committed to improving the quality of life of children in Nigeria, and the rest of the world, by reducing the burden of infectious and related diseases.
Nigeria is the most populated country in Africa and has one of the highest under-five mortality rates in the world. Recent studies have established that invasive bacteria are the leading cause of childhood mortality in Sub-Saharan Africa and that most of these infections are preventable from routine vaccination or proper primary care. Unfortunately, a poor understanding of the magnitude of these bacterial infections and their associated illnesses has not lead to significant advancements in their prevention or treatment.
The International Foundation Against Infectious Disease in Nigeria (IFAIN) was established to facilitate the generation of a credible surveillance system for the determination of the etiologic agents of bacterium syndromes and opportunistic infections in the general population of Nigerian children. Data from these systems are being, and will be, used to development new tests and vaccines as well as to monitor the impact of medical interventions. Of particular interest is the etiology of disease in vulnerable populations, such as children who suffer from human immunodeficiency virus (HIV), sickle-cell disease (SCD) and malnutrition.
Zankli Medical Centre (Nigeria)
Zankli Medical Centre in Abuja is a secondary care medical group practice that provides care in various specialties of Medicine and Surgery and encourages the development of academic and research activities in collaboration with a number of institutions both at home and abroad.
The first High Performance Liquid Chromatography (HPLC) machine for newborn screening for Sickle cell disorder in Nigeria was installed in the Zankli Research laboratory in 2010 during the Sickle cell cohort pilot study funded by the UNDP. Sickle Cell Clinic runs weekly with a trained nurse counsellor. Routine Newborn SCD screening is done in the hospital. Regular immunization and antenatal clinics provide cohort of patients. Reliable X-ray services are available including CT scan, 4D ultrasound scans and full time consultant radiologists. The routine laboratory is well equipped for Microbiology, Chemistry, Haematology and Immunology with BD BACTEC 9050 and FX40 Blood Culture Systems, D10 (Biorad) HPLC machine, Biosafety cabinet, GeneXpert and a variety of other standard lab equipment.
Sickle Cell Cohort Research – Score Foundation (Nigeria)
The Foundation vision is to seek to transform the lives of people living with sickle cell disease in Nigeria and beyond through the implementation of world class research. It aims to build capacity to deliver high quality health care through partnership with local and international organisations.
Azienda Ospedaliera di Padova (Italy)
AOPD is a Tertiary Care University Hospital partnered with the University of Padova and the Medical School of the University of Padova.
The Department of Child and Maternal Health and the Department of Medicine are deeply involved in the care of patients with Haemoglobinopaties and are reference centers in Haematology, Intensive Care, Neurologic Disorders, Bone Marrow Transplantation.
American University of Beirut (Lebanon)
Founded in 1866, the American University of Beirut (AUB), is a private, not-for-profit, coeducational, independent, non-sectarian institution of higher learning operating under a charter from the State of New York and accredited by the Middle States Commission on Higher Education.
The university’s beautiful 73-acre campus overlooking the Mediterranean Sea contains 81 buildings, including a medical center, four libraries, three museums, seven residence halls and an athletic complex.
AUB has more than 66,000 alumni residing in more than 115 countries. It has a tertiary care medical center with 420 beds.
The centre receives more than 360,000 patient visits per year, with 344 physicians, over 1,200 nursing staff and over 1,500 employees. The Department of Pediatrics and Adolescent Medicine provides healthcare services to children and adolescents ages ranging between 0 and 21 years, staffed by around 40 faculty, and 60 residents and fellows.
Institut National de la Sante et de la Recherche Medicale (France)
INSERM is the French public research organization dedicated to human health. Its objective is to promote health by advancing knowledge about life and disease, treatment innovation, and public health research. It operates over 350 research structures across France and abroad, most of them being joint research units with universities.
The Cyprus Foundation for Muscular Dystrophy Research (Cyprus)
The Cyprus Institute of Neurology and Genetics (CING) was established in 1990, as a bi-communal, non-profit, private, medical, research and academic centre. It develops and provides high level medical and clinical laboratory services, advanced research and education in the areas of Neurology, Genetics, Biomedical, Medical and other related sciences.
The Institute is equipped with some of the latest, high-tech laboratory and clinical equipment and its personnel is comprised of 194 individuals, 40 of whom are holders of MD and PhD titles. In 2012 the CING established a postgraduate school, named the Cyprus School of Molecular Medicine (CSMM) offering MSc and PhD degrees.
University College London (UK)
University College London (UCL) Great Ormond Street Institute of Child Health is part of University College London and is closely associated with Great Ormond Street hospital, as well as with most Children’s hospitals and paediatric units throughout the United Kingdom.
The Royal College of Pathologists (UK)
The Royal College of Pathologists (RCPath) is the professional membership organisation and standard setting body for the education, training and professional development of pathologists and scientists in the United Kingdom and around the world. We are committed to setting and maintaining professional standards and to promoting excellence in the practice of pathology and laboratory medicine for the benefit of the public.
University of Illinois at Chicago (USA)
The University of Illinois at Chicago (UIC) is a public research university and the state’s major public medical center including seven colleges in health sciences. Special academic emphases include health disparities, urban transportation, violence prevention, healthcare administration, and ethnic diversity.
The research portfolio spans the full spectrum of translational research, including implementation science, and won the 2018 Orme Award for Community-Academic partnership in research. Training is a strength of the UIC Sickle Cell Center, with over 400 clinical trainees per year and dozens of research mentees. The Center is a leader in the Illinois Department of Public Health newborn screening program and has broad collaboration with sickle cell advocacy organizations.
London School of Hygiene & Tropical Medicine (UK)
The London School of Hygiene & Tropical Medicine (LSHTM) is a world-leading centre for research and postgraduate education in public and global health. Its mission is to is to improve health and health equity in the UK and worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.
Strathmore University (Kenya)
Strathmore University is a private not for profit University in Nairobi, Kenya. The University was founded in 2002 with a mission to provide all round quality education in an atmosphere of freedom and responsibility excellence in teaching, research and scholarship, ethical and social development and service to the society. The University’s key strategic pillars include teaching, research and service to society. Strathmore undergraduate and postgraduate programmes are competitive and of high quality offered to both local and international students.
The University Medical Centre in collaboration with the centre for research in therapeutic sciences runs a Sickle Cell Care Centre that currently has a cohort of 220 patients of all age groups. This is comprehensive Care Clinic is held every Tuesday of the week and has a multidisciplinary team comprising of paediatricians, physicians, haematologist, psychologist, physical therapists, surgeons, dentists, ophthalmologist and peer patient educators. This is to enable provision of all-round care of the patients without having to shuttle the patients across different clinics that can lead to loss to follow up.
Ahmadu Bello University (Nigeria)
Ahmadu Bello University (ABU) is a federal government research university located in Zaria, Kaduna State, founded in 1962, as the University of Northern Nigeria. The university operates three main campuses: Samaru and Kongo in Zaria, and School of Basic Studies in Funtua. Additionally, the university is responsible for a variety of other institutions and programs at other locations.
The university runs a wide variety of undergraduate and graduate programs (and offers associate degrees and vocational and remedial programs). The university has a large medical program with its own ABU Teaching Hospital, one of the largest teaching hospitals in Nigeria and Africa. ABU can claim to be the largest and the most extensive of universities in Sub-Saharan Africa. It has five institutes, six specialized centers, a Division of Agricultural Colleges, demonstration secondary and primary schools, as well as extension and consultancy services which provide a variety of services to the wider society. The total student enrolment in the university’s degree and sub-degree programs is about 35,000, drawn from every state of Nigeria, from Africa and from the rest of world. There are about 1,400 academic and research staff and 5,000 support staff.
The Department of Geography is among the oldest departments of Geography in the country and one of the original departments that formed the nucleus of Ahmadu Bello University in 1962. On September 26, 1962, the rooms formally used for teaching ‘A’ level geography at the former Nigerian College of arts, Science and Technology (which later became ABU), became the nucleus of the University’s department of geography and has remained so ever since, although greatly expanded. The department plays its traditional roles of teaching, research and community service in both physical and Human Geography.
The ARISE project is been coordinated by the Department of Geography, Ahmadu Bello University, Zaria. The department has been a major player conducting studies and researches on terrain analysis, disaster environmental management. Epidemiology and disease mapping
One of the missions of the department of Geography, ABU, Zaria, is set out to advance the frontier of knowledge in geography through teaching and research by employing the state-of-the-art technology in the process and to be in the state of preparedness to render service to the community whenever called upon through applied geographical research.
The department currently runs the following programmes:
- Undergraduate- all aspects of physical and human geography
- Postgraduate Diplomas in Remote Sensing and GIS
- Postgraduate Diplomas in Rural Geography
- Postgraduate (M.Sc. & Ph.D – Environmental Management, Remote Sensing and GIS, Population and Demographic studies with emphasis on Reproductive Health, Medical Geography with emphasis on Communicable and non-communicable diseases and inherited diseases)
The Department has conducted the following researches such as:
- The study and mapping of Disaster Vulnerability and Capacity Analysis in the Federal Capital Territory, Abuja (2008-2009)
- The establishment of a Databank For Disaster Management Information system in the Federal Capital Territory, Abuja (2010-2011)
- Sickle cell Cohort Research Foundation
The affiliated teaching hospital is responsible for training of highest quality doctors, paramedics and allied health sciences at all levels through engagements in research and community service delivery. Ahmadu Bello University Teaching Hospital (ABUTH) is an affiliated teaching hospital that is responsible for the training of highest quality doctors, paramedics and allied health sciences at all levels through engagements in research and community service delivery.
Kaduna State University (Nigeria)
Kaduna State University is a state-owned and funded public university operational since 2004 in the state capital and Kafanchan campus, Makera campus is latest among the campuses. It offers a number of undergraduate and postgraduate degree and non-degree programs in the arts, sciences and humanities.
The College has since inception secured academic and professional accreditation and is poised to graduate its first alumni within the next calendar year.
The young College is research driven and has successfully secured national grants from the Tertiary Education Trust Fund (TETFUND) and is involved in collaborative research with international partners in the United States, United Kingdom, Asia and other parts of Africa.
Kaduna State Assembly (Nigeria)
The Kaduna State House of Assembly is the Legislative arm of the Government of Kaduna State it has 34 elected Legislators representing various constituencies across the State. The Legislature is empowered by the Constitution of the Federal Republic of Nigeria and it has the responsibility of making, amending and repealing laws that will improve on the wellbeing of the residents of Kaduna State.
PANAF schools (Nigeria)
PANAF Schools is a private Nursery, Primary, Secondary School and Cambridge A level Centre. It opened its doors to students on the 11th September 2000 and offers Education to children between the ages of 2-17 years with an integrated curriculum; Nigerian, British and Montessori methods.
PANAF provides an academically challenging and competitive environment, two teachers per class in the junior school with a maximum of 25-30 pupils/students. The classes ensure personal involvement in each child’s progress which also assists in instilling and nurturing the desire to learn.
The mission of the school is to nurture each student in a moral environment with trained faculties of mentors and teaching aids and the Vision of the school is to become the preferred educational institution for developing emotionally intelligent entrepreneurial leaders. With core values of passion, attitude, nurturing, affirmation and fairness, PANAF thrives with an all-inclusive programme that allows teachers and students achieve their intellectual pursuits, dreams and passions.
At PANAF, discipline and ensuring that students not only learn literacy and numeracy but skills that go beyond the classroom and which expose them to entrepreneurship with a deliberate intension that they grow to be independent solution providers, job creators and employers of labour is the goal.
PANAF premises is owned independently by the Director of the school. It is not rented or co-owned with another organisation, is a good research ground and has accepted to collaborate with this research for the success of the project.
Barau Dikko Teaching Hospital (Nigeria)
Barau Dikko Teaching Hospital (BDTH) was established by law in March 2015 but had existed since 1930 previously as Nursing Home, then as the New General Hospital and subsequently as Barau Dikko Teaching Hospital.
It is affiliated to the College of Medicine, Kaduna State University and provides tertiary health care to the over four million strong population in Kaduna city and its environs, with an in-patient capacity of 240 beds. It also serves as one of the referral centers for the North Western region of Nigeria.
The facility boasts state-of-the-art radio-diagnostics, a fledging in-vitro fertilization service, a strong research base in the basic clinical sciences where through the department of haematology and blood transfusion, it is in collaboration with other institutions for the study of primary stroke prevention in Sickle cell disease (SPRING trial) and the Sickle Pan-African research consortium (SPARCO). It is also the North west regional training centre for transcranial doppler.
The hospital has a specialist clinic that manages sickle cell disease with a combined enrolment of both paediatrics and adult sickle cell patients at about 4000.
With a four-pronged mission agenda in research, training, service delivery and medical enterprise, the institution competes favorably with other more established tertiary institutions in the region.
The rapidly growing Teaching Hospital has attracted international attention in various specialties, notably in the fields of sickle cell research and intervention initiatives.